Is it safe to eat grapefruit while taking a statin? Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Why is grapefruit not good with medication? Others may need to consume more of the fruit or juice to have an interaction. Just one grapefruit or one glass of grapefruit juice could be enough to cause an interaction in some people. The exact amount of grapefruit it takes to have a negative reaction when taking lovastatin, atorvastatin, or simvastatin is unknown. How much grapefruit is safe with atorvastatin? When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects. Grapefruit contains a chemical that can interfere with your body’s ability to break down or metabolize certain statin medications. What happens if you eat grapefruit with cholesterol medicine? The time that you take one of these medications and the time that you eat grapefruit or drink grapefruit juice does not reduce your risk of drug-related adverse effects–-an interaction can happen up to three days after consuming grapefruit. How long after taking atorvastatin can you eat grapefruit? 6 What kind of medications can you take with grapefruit juice?.5 What happens if you eat a grapefruit while taking medication?.4 Is it safe to eat grapefruit while taking a statin?.3 Why is grapefruit not good with medication?.2 What happens if you eat grapefruit with cholesterol medicine?.1 How long after taking atorvastatin can you eat grapefruit?.
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